height.scores: Genetic risk score for height.
In gtx: Genetics ToolboX

Description Usage Format Source

Risk score for height parameterised using GWAS meta-analysis results published by Lango Allen et al. (Nature 2010) as part of work by the GIANT consortium.

1	data(height.scores)

A data frame suitable for use with other functions in this package, see gtx.params.

The score is called HEIGHT2010, and has coefficients in height Z score units (i.e. phenotypic standard deviations) per coded allele. One phenotypic standard deviation for height is 0.06-0.07m in most samples analysed by Lango Allen et al.

Effect size estimates are taken from the “STAGE 2” results in Supplementary Table 1 of Lango Allen et al.

For the publication by Lango Allen et al. from which these data were extracted see http://dx.doi.org/10.1038/nature09410.

gtx documentation built on May 2, 2019, 5:08 a.m.