snphwe: Exact test of Hardy-Weinberg.
In gtx: Genetics ToolboX

Description Usage Arguments Details Value Author(s) Examples

Computes a p-value for the exact test of Hardy–Weinberg proportions, for genotype counts for a biallelic locus, as described by Wiggington et al. (2005)

snphwe(g)

`g`	Vector of genotypes.

This function is a wrapper for snphweCounts, which uses code by Wiggington et al. to compute a P-value for an exact test of Hardy–Weinberg proportions.

This function requires that when g is sorted, the order is hom/het/hom. For example g can be additively coded genotypes (0, 1, 2), or text coded genotypes like AA, AC, CC. For text coded genotypes the heterozygote MUST ALWAYS be coded the same way, e.g. a mixture of AC and CA are not allowed.

The p-value.

Toby Johnson Toby.x.Johnson@gsk.com