check_model: Check for sufficient model parameters
In httk: High-Throughput Toxicokinetics

check_model

R Documentation

Check for sufficient model parameters

Description

This function halt model evaluation if not all the needed parameters (as specified in the modelinfo_[MODEL].r file) are available. The function uses get_cheminfo, so if the chemical has been checked against that function already then evaluation should proceed as expected. If you do not have the parameters you need and are using a non-human species try default.to.human = TRUE (there are many more values for human than any other species). If working in human, try first using load_dawson2021, load_sipes2017, or load_pradeep2020.

Usage

check_model(
  chem.name = NULL,
  chem.cas = NULL,
  dtxsid = NULL,
  model = NULL,
  species = NULL,
  class.exclude = TRUE,
  default.to.human = FALSE
)

Arguments

`chem.name`	Chemical name (spaces and capitalization ignored) – if parameters is not specified then the chemical must be identified by either CAS, name, or DTXISD
`chem.cas`	Chemical Abstract Services Registry Number (CAS-RN) – if parameters is not specified then the chemical must be identified by either CAS, name, or DTXISD
`dtxsid`	EPA's DSSTox Structure ID (https://comptox.epa.gov/dashboard) – if parameters is not specified then the chemical must be identified by either CAS, name, or DTXSIDs
`model`	Model to be checked, modelinfo files specify the requrements of each model.
`species`	Species desired (either "Rat", "Rabbit", "Dog", "Mouse", or default "Human").
`class.exclude`	Exclude chemical classes identified as outside of domain of applicability by relevant modelinfo_[MODEL] file (default TRUE).
`default.to.human`	Substitutes missing fraction of unbound plasma with human values if true.