estimate_hematocrit: Generate hematocrit values for a virtual population

In httk: High-Throughput Toxicokinetics

Generate hematocrit values for a virtual population

Description

Predict hematocrit from age using smoothing splines and kernel density estimates of residual variability fitted to NHANES data, for a given combination of gender and NHANES race/ethnicity category.

Usage

estimate_hematocrit(gender, reth, age_years, age_months, nhanes_mec_svy)

Arguments

gender	Gender for which to generate hematocrit values ("Male" or "Female")
reth	NHANES race/ethnicity category for which to generate serum creatinine values ("Mexican American", "Non-Hispanic Black", "Non-Hispanic White", "Other", or "Other Hispanic")
age_years	Vector of ages in years for individuals for whom to generate hematocrit values (corresponding to age_months)
age_months	vector of ages in months for individuals for whom to generate hematocrit values (between 0-959 months)
nhanes_mec_svy	surveydesign object created from mecdt using svydesign (this is done in httkpop_generate)

Details

This function should usually not be called directly by the user. It is used by httkpop_generate() in "virtual-individuals" mode, after drawing gender, NHANES race/ethnicity category, and age from their NHANES proportions/distributions.

Value

A vector of numeric generated hematocrit values (blood percentage red blood cells by volume).

Author(s)

Caroline Ring

References

Ring, Caroline L., et al. "Identifying populations sensitive to environmental chemicals by simulating toxicokinetic variability." Environment International 106 (2017): 105-118

httk documentation built on March 7, 2023, 7:26 p.m.