get_invitroPK_param: Retrieve species-specific in vitro data from...

In httk: High-Throughput Toxicokinetics

Retrieve species-specific in vitro data from chem.physical_and_invitro.data table

Description

This function retrieves in vitro PK data (for example intrinsic metabolic clearance or fraction unbound in plasma) from the main HTTK data. This function looks for species-specific values.

Usage

get_invitroPK_param(
  param,
  species,
  chem.name = NULL,
  chem.cas = NULL,
  dtxsid = NULL
)

Arguments

param	The in vitro pharmacokinetic parameter needed.
species	Species desired (either "Rat", "Rabbit", "Dog", "Mouse", or default "Human").
chem.name	Either the chemical name, CAS number, or the parameters must be specified.
chem.cas	Either the chemical name, CAS number, or the parameters must be specified.
dtxsid	EPA's DSSTox Structure ID (https://comptox.epa.gov/dashboard) the chemical must be identified by either CAS, name, or DTXSIDs

Details

Note that this function works with a local version of the get.physical_and_invitro.data table to allow users to add/modify chemical data (for example, via add_chemtable or load_sipes2017).

Value

The value of the parameter, if found

Author(s)

John Wambaugh and Robert Pearce

See Also

get_physchem_param

httk documentation built on March 7, 2023, 7:26 p.m.