# binregATE: Average Treatment effect for censored competing risks data... In mets: Analysis of Multivariate Event Times

 binregATE R Documentation

## Average Treatment effect for censored competing risks data using Binomial Regression

### Description

Under the standard causal assumptions we can estimate the average treatment effect E(Y(1) - Y(0)). We need Consistency, ignorability ( Y(1), Y(0) indep A given X), and positivity.

### Usage

```binregATE(
formula,
data,
cause = 1,
time = NULL,
beta = NULL,
treat.model = ~+1,
cens.model = ~+1,
offset = NULL,
weights = NULL,
cens.weights = NULL,
se = TRUE,
kaplan.meier = TRUE,
cens.code = 0,
no.opt = FALSE,
method = "nr",
augmentation = NULL,
outcome = c("cif", "rmst", "rmst-cause"),
model = "exp",
Ydirect = NULL,
...
)
```

### Arguments

 `formula` formula with outcome (see `coxph`) `data` data frame `cause` cause of interest `time` time of interest `beta` starting values `treat.model` logistic treatment model given covariates `cens.model` only stratified cox model without covariates `offset` offsets for partial likelihood `weights` for score equations `cens.weights` censoring weights `se` to compute se's with IPCW adjustment, otherwise assumes that IPCW weights are known `kaplan.meier` uses Kaplan-Meier for IPCW in contrast to exp(-Baseline) `cens.code` gives censoring code `no.opt` to not optimize `method` for optimization `augmentation` to augment binomial regression `outcome` can do CIF regression "cif"=F(t|X), "rmst"=E( min(T, t) | X) , or "rmst-cause"=E( I(epsilon==cause) ( t - mint(T,t)) ) | X) `model` possible exp model for E( min(T, t) | X)=exp(X^t beta) , or E( I(epsilon==cause) ( t - mint(T,t)) ) | X)=exp(X^t beta) `Ydirect` use this Y for fitting G model set outcome to "rmst" to fit using the model specified by model `...` Additional arguments to lower level funtions

### Details

The first covariate in the specification of the competing risks regression model must be the treatment effect that is a factor. If the factor has more than two levels then it uses the mlogit for propensity score modelling. If there are no censorings this is the same as ordinary logistic regression modelling.

Estimates the ATE using the the standard binary double robust estimating equations that are IPCW censoring adjusted. Rather than binomial regression we also consider a IPCW weighted version of standard logistic regression logitIPCWATE.

The original version of the program with only binary treatment binregATEbin take binary-numeric as input for the treatment, and also computes the ATT and ATC, average treatment effect on the treated (ATT), E(Y(1) - Y(0) | A=1), and non-treated, respectively. Experimental version.

Thomas Scheike

### Examples

```data(bmt)
dfactor(bmt)  <-  ~.

brs <- binregATE(Event(time,cause)~tcell.f+platelet+age,bmt,time=50,cause=1,
treat.model=tcell.f~platelet+age)
summary(brs)

brsi <- binregATE(Event(time,cause)~tcell.f+tcell.f*platelet+tcell.f*age,bmt,time=50,cause=1,
treat.model=tcell.f~platelet+age)
summary(brsi)

```

mets documentation built on Jan. 17, 2023, 5:12 p.m.