ncappc: NCA Calculation and Population PK Model Diagnosis

A flexible tool is presented here that can perform (i) traditional non-compartmental analysis (NCA) and (ii) simulation-based posterior predictive checks for a population pharmacokinetic (PK) model using NCA metrics.

Install the latest version of this package by entering the following in R:
install.packages("ncappc")
AuthorChayan Acharya [aut, cre], Andrew C. Hooker [aut], Siv Jonsson [aut], Mats O. Karlsson [aut]
Date of publication2016-02-17 10:52:17
MaintainerChayan Acharya <chayan.acharya@farmbio.uu.se>
LicenseGPL-3
Version0.2.1.1

View on CRAN

Files

inst
inst/examples
inst/examples/example1.R
inst/CITATION
inst/misc
inst/misc/ncappcReport-NCA.Rnw
inst/misc/ncappcReport-NCA.Rmd
inst/misc/ncappcReport-NCA-PPC.Rmd
inst/misc/ncappcReport-NCA-PPC.Rnw
inst/misc/custom.css
inst/misc/makeLatexRepresentativeDataTable.R
inst/extdata
inst/extdata/pkdata.csv
inst/doc
inst/doc/ncappc-vignette.R
inst/doc/ncappc-vignette.Rmd
inst/doc/ncappc-vignette.html
tests
tests/testthat
tests/testthat/ncappcexamples
tests/testthat/ncappcexamples/example1.R tests/testthat/test-ncappc.R tests/testthat/testthat.R
NAMESPACE
R
R/est.nca.R R/nca.pde.deviation.outlier.R R/nca.npde.R R/histobs.plot.R R/ncappc.R R/nca.npde.plot.R R/calc.stat.R R/read_nm_table.R R/histpop.plot.R R/dv.plot.R R/nca.deviation.plot.R
vignettes
vignettes/histobs.png
vignettes/conc.jpeg
vignettes/Deviation-vgn.png
vignettes/Sub-EstimatedNCAmetrics.Rmd
vignettes/ncappc_Schema.tif
vignettes/conc-vgn.png
vignettes/Outlier-vgn.png
vignettes/popmean.png
vignettes/ncappc-vignette.txt
vignettes/ncappc_Schema.png
vignettes/Sub-CommandLineArguments.Rmd
vignettes/outlier.png
vignettes/NPDE-vgn.png
vignettes/histNPDE-vgn.png
vignettes/ncappc-vignette.Rmd
vignettes/popMean-vgn.png
vignettes/deviation.png
vignettes/ncappc-vignette.md
vignettes/Sub-Output.Rmd
vignettes/HistObs-vgn.png
vignettes/forest-vgn.png
vignettes/Sub-EstimationMethod.Rmd
vignettes/forest.png
vignettes/npde.png
vignettes/ncappc-Schema.png
vignettes/histnpde.png
README.md
MD5
build
build/vignette.rds
DESCRIPTION
man
man/calc.stat.Rd man/nca.npde.Rd man/nca.pde.deviation.outlier.Rd man/dv.plot.Rd man/histobs.plot.Rd man/read_nm_table.Rd man/nca.deviation.plot.Rd man/nca.npde.plot.Rd man/est.nca.Rd man/ncappc.Rd man/histpop.plot.Rd
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