ncappc: NCA Calculation and Population PK Model Diagnosis

A flexible tool is presented here that can perform (i) traditional non-compartmental analysis (NCA) and (ii) simulation-based posterior predictive checks for a population pharmacokinetic (PK) model using NCA metrics.

AuthorChayan Acharya [aut, cre], Andrew C. Hooker [aut], Siv Jonsson [aut], Mats O. Karlsson [aut]
Date of publication2016-02-17 10:52:17
MaintainerChayan Acharya <chayan.acharya@farmbio.uu.se>
LicenseGPL-3
Version0.2.1.1

View on CRAN

Files

ncappc
ncappc/inst
ncappc/inst/examples
ncappc/inst/examples/example1.R
ncappc/inst/CITATION
ncappc/inst/misc
ncappc/inst/misc/ncappcReport-NCA.Rnw
ncappc/inst/misc/ncappcReport-NCA.Rmd
ncappc/inst/misc/ncappcReport-NCA-PPC.Rmd
ncappc/inst/misc/ncappcReport-NCA-PPC.Rnw
ncappc/inst/misc/custom.css
ncappc/inst/misc/makeLatexRepresentativeDataTable.R
ncappc/inst/extdata
ncappc/inst/extdata/pkdata.csv
ncappc/inst/doc
ncappc/inst/doc/ncappc-vignette.R
ncappc/inst/doc/ncappc-vignette.Rmd
ncappc/inst/doc/ncappc-vignette.html
ncappc/tests
ncappc/tests/testthat
ncappc/tests/testthat/ncappcexamples
ncappc/tests/testthat/ncappcexamples/example1.R
ncappc/tests/testthat/test-ncappc.R
ncappc/tests/testthat/testthat.R
ncappc/NAMESPACE
ncappc/R
ncappc/R/est.nca.R ncappc/R/nca.pde.deviation.outlier.R ncappc/R/nca.npde.R ncappc/R/histobs.plot.R ncappc/R/ncappc.R ncappc/R/nca.npde.plot.R ncappc/R/calc.stat.R ncappc/R/read_nm_table.R ncappc/R/histpop.plot.R ncappc/R/dv.plot.R ncappc/R/nca.deviation.plot.R
ncappc/vignettes
ncappc/vignettes/histobs.png
ncappc/vignettes/conc.jpeg
ncappc/vignettes/Deviation-vgn.png
ncappc/vignettes/Sub-EstimatedNCAmetrics.Rmd
ncappc/vignettes/ncappc_Schema.tif
ncappc/vignettes/conc-vgn.png
ncappc/vignettes/Outlier-vgn.png
ncappc/vignettes/popmean.png
ncappc/vignettes/ncappc-vignette.txt
ncappc/vignettes/ncappc_Schema.png
ncappc/vignettes/Sub-CommandLineArguments.Rmd
ncappc/vignettes/outlier.png
ncappc/vignettes/NPDE-vgn.png
ncappc/vignettes/histNPDE-vgn.png
ncappc/vignettes/ncappc-vignette.Rmd
ncappc/vignettes/popMean-vgn.png
ncappc/vignettes/deviation.png
ncappc/vignettes/ncappc-vignette.md
ncappc/vignettes/Sub-Output.Rmd
ncappc/vignettes/HistObs-vgn.png
ncappc/vignettes/forest-vgn.png
ncappc/vignettes/Sub-EstimationMethod.Rmd
ncappc/vignettes/forest.png
ncappc/vignettes/npde.png
ncappc/vignettes/ncappc-Schema.png
ncappc/vignettes/histnpde.png
ncappc/README.md
ncappc/MD5
ncappc/build
ncappc/build/vignette.rds
ncappc/DESCRIPTION
ncappc/man
ncappc/man/calc.stat.Rd ncappc/man/nca.npde.Rd ncappc/man/nca.pde.deviation.outlier.Rd ncappc/man/dv.plot.Rd ncappc/man/histobs.plot.Rd ncappc/man/read_nm_table.Rd ncappc/man/nca.deviation.plot.Rd ncappc/man/nca.npde.plot.Rd ncappc/man/est.nca.Rd ncappc/man/ncappc.Rd ncappc/man/histpop.plot.Rd

Questions? Problems? Suggestions? or email at ian@mutexlabs.com.

Please suggest features or report bugs with the GitHub issue tracker.

All documentation is copyright its authors; we didn't write any of that.