Plots histogram of selected set of NCA metrics.

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Description

histobs.plot plots histogram of selected set of NCA metrics (e.g. AUClast, AUCINF_obs, Cmax and Tmax).

Usage

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histobs.plot(plotData, figlbl = NULL, param = c("AUClast", "AUCINF_obs",
  "Cmax", "Tmax"), cunit = "[M].[L]^-3", tunit = "[T]", spread = "npi")

Arguments

plotData

A data frame with the estimated NCA metrics

figlbl

Figure label based on dose identifier and/or population stratifier (NULL)

param

A character array of the NCA metrics. The allowed NCA metrics for this histograms are "AUClast", "AUClower_upper", "AUCINF_obs", "AUCINF_pred", "AUMClast", "Cmax", "Tmax" and "HL_Lambda_z". (c("AUClast", "AUCINF_obs", "Cmax", "Tmax"))

cunit

Unit for concentration ("[M].[L]^-3")

tunit

Unit for time ("[T]")

spread

Measure of the spread of simulated data (ppi (95% parametric prediction interval) or npi (95% nonparametric prediction interval)) ("npi")

Details

histobs.plot plots histogram of selected set of NCA metrics. The allowed NCA metrics for this histograms are "AUClast", "AUClower_upper", "AUCINF_obs", "AUCINF_pred", "AUMClast", "Cmax", "Tmax" and "HL_Lambda_z". By default, this function produces histogram of AUClast, AUCINF_obs, Cmax and Tmax.

Value

returns a graphical object created by arrangeGrob function