nca.check.sim: Check simulated data
In ncappc: NCA Calculations and Population Model Diagnosis

Description Usage Arguments Details Value

nca.check.sim Checks simulated data for compatibility with ncappc and processes the data with various filtering criteria.

nca.check.sim(simData, idNmSim = "ID", timeNmSim = "TIME",
  concNmSim = "DV", filterNm = NULL, filterExcl = NULL,
  str1Nm = NULL, str1 = NULL, str2Nm = NULL, str2 = NULL,
  str3Nm = NULL, str3 = NULL, adminType = "extravascular",
  TI = NULL, doseAmtNm = NULL, blqNm = NULL, blqExcl = 1,
  evid = TRUE, evidIncl = 0, mdv = FALSE)

`simData`	Simulated concentration-time data.
`idNmSim`	Column name for ID in simulated data. Default is "ID"
`timeNmSim`	Column name for time in simulated data. Default is "TIME"
`concNmSim`	Column name for concentration in simulated data. Default is "DV"
`filterNm`	Column name to filter data. Default is `NULL`
`filterExcl`	Row exclusion criteria based on the column defined by `filterNm`. This can be numeric value or logical condition (e.g. c(1, 2, "<20", ">=100", "!=100")). Default is `NULL`
`str1Nm`	Column name for 1st level population stratifier. Default is `NULL`
`str1`	Stratification ID of the members within 1st level stratification (e.g c(1,2)). Default is `NULL`
`str2Nm`	Column name for 2nd level population stratifier. Default is `NULL`
`str2`	Stratification ID of the members within 2nd level stratification (e.g c(1,2)). Default is `NULL`
`str3Nm`	Column name for 3rd level population stratifier. Default is `NULL`
`str3`	Stratification ID of the members within 3rd level stratification (e.g c(1,2)). Default is `NULL`
`adminType`	Route of administration. Allowed options are iv-bolus, iv-infusion or extravascular. Default is "extravascular"
`TI`	Infusion duration. If TI is a single numeric value, TI is the same for all individuals. If TI is the name of a column with numeric data present in the data set, TI is set to the unique value of the column for a given individual. Default is `NULL`
`doseAmtNm`	Column name to specify dose amount. Default is `NULL`
`blqNm`	Name of BLQ column if used to exclude data. Default is `NULL`
`blqExcl`	Excluded BLQ value; either a numeric value or a logical condition (e.g. 1 or ">=1" or c(1,">3")). Used only if the `blqNm` is not `NULL`. Default is "1"
`evid`	If `TRUE` EVID is used to filter data. Default is `TRUE`
`evidIncl`	Included values in EVID. Default is "0"
`mdv`	If `TRUE` MDV is used to include data when MDV=0. Default is `FALSE`