nca.ind.data: Prepare individual PK data

In ncappc: NCA Calculations and Population Model Diagnosis

Description

nca.ind.data Extracts time-conc data for a given individual.

Usage

nca.ind.data(pkData, ID, dvLog = FALSE, dataType = "obs",
  idNm = "ID", timeNm = "TIME", concNm = "DV",
  adminType = "extravascular", TI = NULL, dateColNm = NULL,
  dateFormat = NULL, timeFormat = "number")

Arguments

pkData	PK concentration-time data.
ID	ID number of the individual.
dvLog	If TRUE concentration is in logarithmic scale. Default is FALSE
dataType	Indicates if the data is observed ("obs") or simulated ("sim"). Since the simulated data is assumed to be obtained from NONMEM output, DATE and clock time (dateColNm, dateFormat, timeFormat) are not used for time data. Default is "obs".
idNm	Column name for ID in PK data. Default is "ID"
timeNm	Column name for time in PK data. Default is "TIME"
concNm	Column name for concentration in PK data. Default is "DV"
adminType	Route of administration. Allowed options are iv-bolus, iv-infusion or extravascular. Default is "extravascular"
TI	Infusion duration. If TI is a single numeric value, TI is the same for all individuals. If TI is the name of a column with numeric data present in the data set, TI is set to the unique value of the column for a given individual. Default is NULL
dateColNm	column name for date if used (e.g. "Date", "DATE"). Default is NULL
dateFormat	date format (D-M-Y, D/M/Y or any other combination of D,M,Y). Default is NULL
timeFormat	time format (number, H:M, H:M:S). Default is "number"

Details

nca.ind.data Extracts time-conc data for a given individual.

Value

A list of objects with time-conc data and individual infusion duration for iv-infusion data

ncappc documentation built on May 1, 2019, 7:31 p.m.