Nothing
#' Search Proteomics Peptides in UniProt (Deprecated)
#'
#' This function is Deprecated. Please use
#' \code{\link{rba_uniprot_proteomics_non_ptm_search}} instead.\cr
#' UniProt maps proteomics peptides from different sources to the proteins'
#' sequences. Using this function, you can search for proteomics
#' peptides that has been map to UniProt proteins. You may also refine your
#' search with modifiers such as data_source, peptide etc. See
#' "Arguments section" for more information.
#'
#' Note that this is a search function. Thus, you are not required to fill
#' every argument; You may use whatever combinations of arguments you see
#' fit for your query.
#' \cr see also: \href{https://www.uniprot.org/help/proteomics}{Mass
#' spectrometry-based proteomics data in UniProtKB}
#'
#' @section Corresponding API Resources:
#' "GET https://www.ebi.ac.uk/proteins/api/proteomics"
#'
#' @param accession \href{https://www.uniprot.org/help/accession_numbers}{
#' UniProtKB primary or secondary accession}(s). You can supply up to 100
#' accession numbers.
#' @param data_source Proteomics data source. You can choose up to two of:
#' \itemize{
#' \item \href{https://www.uniprot.org/database/DB-0186}{"MaxQB"}
#' \item \href{https://www.uniprot.org/database/DB-0071}{"PeptideAtlas"}
#' \item \href{https://www.uniprot.org/database/DB-0205}{"EPD"}
#' \item \href{https://www.uniprot.org/database/DB-0229}{"ProteomicsDB"}
#' }
#' @param taxid NIH-NCBI \href{https://www.uniprot.org/taxonomy/}{Taxon ID}.
#' You can supply up to 20 taxon IDs.
#' @param upid \href{https://www.uniprot.org/help/proteome_id}{UniProt Proteome
#' identifier (UPID)}. You can supply up to 100 UPIDs.
#' @param peptide Peptide sequence(s). You can supply up to 20 sequences.
#' @param unique Logical: Should the results be filtered based on the
#' Peptide's uniqueness (the fact that a peptide maps to only 1 protein). If
#' TRUE, Only unique peptides will be returned, if FALSE only un-unique
#' peptides will be returned; If NULL (default) the results will not be
#' filtered based on this.
#' @param ... rbioapi option(s). See \code{\link{rba_options}}'s
#' arguments manual for more information on available options.
#'
#' @return A list Where each element correspond to a UniProt protein and
#' proteomics peptides are organized under the "features" sub-list.
#'
#' @references \itemize{
#' \item The UniProt Consortium, UniProt: the universal protein
#' knowledgebase in 2021, Nucleic Acids Research, Volume 49, Issue D1,
#' 8 January 2021, Pages D480–D489, https://doi.org/10.1093/nar/gkaa1100
#' \item Andrew Nightingale, Ricardo Antunes, Emanuele Alpi, Borisas
#' Bursteinas, Leonardo Gonzales, Wudong Liu, Jie Luo, Guoying Qi, Edd
#' Turner, Maria Martin, The Proteins API: accessing key integrated protein
#' and genome information, Nucleic Acids Research, Volume 45, Issue W1,
#' 3 July 2017, Pages W539–W544, https://doi.org/10.1093/nar/gkx237
#' \item \href{https://www.ebi.ac.uk/proteins/api/doc/}{Proteins API
#' Documentation}
#' \item \href{https://www.uniprot.org/help/publications}{Citations note
#' on UniProt website}
#' }
#'
#' @examples
#' \dontrun{
#' #Deprecated
#' rba_uniprot_proteomics_search(peptide = "MEDYTKIEK")
#' }
#' \dontrun{
#' #Deprecated
#' rba_uniprot_proteomics_search(peptide = "MEDYTKIEK")
#' }
#' \dontrun{
#' #Deprecated
#' ### this will generate a very large response!
#' rba_uniprot_proteomics_search(taxid = 9606,
#' data_source = "PeptideAtlas",
#' progress = TRUE, timeout = 999999, unique = TRUE)
#' }
#'
#' @family "Deprecated functions"
#' @export
rba_uniprot_proteomics_search <- function(accession = NULL,
data_source = NULL,
taxid = NULL,
upid = NULL,
peptide = NULL,
unique = NULL,
...) {
.Deprecated(new = "rba_uniprot_proteomics_non_ptm_search")
## Load Global Options
.rba_ext_args(...)
## Check User-input Arguments
.rba_args(
cons = list(
list(arg = "accession", class = "character", max_len = 100),
list(arg = "taxid", class = "numeric", max_len = 20),
list(arg = "upid", class = "character", max_len = 100),
list(
arg = "data_source", class = "character", max_len = 2,
vals = c("MaxQB", "PeptideAtlas", "EPD", "ProteomicsDB")
),
list(arg = "peptide", class = "character", max_len = 20),
list(arg = "unique", class = "logical")
)
)
.msg(
"Searching UniProt and retrieving proteomics peptides features of proteins that match your supplied inputs."
)
## Build GET API Request's query
call_query <- .rba_query(
init = list("size" = "-1"),
list("accession", !is.null(accession), paste0(accession, collapse = ",")),
list("taxid", !is.null(taxid), paste0(taxid, collapse = ",")),
list("upid", !is.null(upid), paste0(upid, collapse = ",")),
list("data_source", !is.null(data_source), paste0(data_source, collapse = ",")),
list("peptide", !is.null(peptide), paste0(peptide, collapse = ",")),
list("unique", !is.null(unique), ifelse(unique, "true", "false"))
)
## Build Function-Specific Call
parser_input <- list("json->list", .rba_uniprot_search_namer)
input_call <- .rba_httr(
httr = "get",
url = .rba_stg("uniprot", "url"),
path = paste0(.rba_stg("uniprot", "pth"), "proteomics"),
query = call_query,
accept = "application/json",
parser = parser_input,
save_to = .rba_file("uniprot_proteomics_search.json")
)
## Call API
final_output <- .rba_skeleton(input_call)
return(final_output)
}
#' Get Proteomics Peptides Mapped to UniProt Protein (Deprecated)
#'
#' This function is Deprecated. Please use
#' \code{\link{rba_uniprot_proteomics_non_ptm}} instead.\cr
#' UniProt maps proteomics peptides from different sources to the proteins'
#' sequences. Using this function, you can retrieve all the proteomics
#' peptides features that has been map to a given UniProt protein's sequence.
#'
#' @section Corresponding API Resources:
#' "GET https://www.ebi.ac.uk/proteins/api/proteomics/\{accession\}"
#'
#' @param accession \href{https://www.uniprot.org/help/accession_numbers}{
#' UniProtKB primary or secondary accession}.
#' @param ... rbioapi option(s). See \code{\link{rba_options}}'s
#' arguments manual for more information on available options.
#'
#' @return A list containing the proteomics peptides features of your supplied
#' UniProt protein's sequence.
#'
#' @references \itemize{
#' \item The UniProt Consortium, UniProt: the universal protein
#' knowledgebase in 2021, Nucleic Acids Research, Volume 49, Issue D1,
#' 8 January 2021, Pages D480–D489, https://doi.org/10.1093/nar/gkaa1100
#' \item Andrew Nightingale, Ricardo Antunes, Emanuele Alpi, Borisas
#' Bursteinas, Leonardo Gonzales, Wudong Liu, Jie Luo, Guoying Qi, Edd
#' Turner, Maria Martin, The Proteins API: accessing key integrated protein
#' and genome information, Nucleic Acids Research, Volume 45, Issue W1,
#' 3 July 2017, Pages W539–W544, https://doi.org/10.1093/nar/gkx237
#' \item \href{https://www.ebi.ac.uk/proteins/api/doc/}{Proteins API
#' Documentation}
#' \item \href{https://www.uniprot.org/help/publications}{Citations note
#' on UniProt website}
#' }
#'
#' @examples
#' \dontrun{
#' #Deprecated
#' rba_uniprot_proteomics(accession = "P25942")
#' }
#'
#' @family "Deprecated functions"
#' @export
rba_uniprot_proteomics <- function(accession,
...) {
.Deprecated("rba_uniprot_proteomics_non_ptm")
## Load Global Options
.rba_ext_args(...)
## Check User-input Arguments
.rba_args(
cons = list(
list(arg = "accession", class = "character", len = 1)
)
)
.msg(
"Retrieving proteomics peptides features mapped to the sequence of protein %s.",
accession
)
## Build Function-Specific Call
input_call <- .rba_httr(
httr = "get",
url = .rba_stg("uniprot", "url"),
path = paste0(.rba_stg("uniprot", "pth"), "proteomics/", accession),
accept = "application/json",
parser = "json->list",
save_to = .rba_file("uniprot_proteomics.json")
)
## Call API
final_output <- .rba_skeleton(input_call)
return(final_output)
}
#' Search Post-Translational Modification in UniProt (Deprecated)
#'
#' This function is Deprecated. Please use
#' \code{\link{rba_uniprot_proteomics_ptm_search}} instead.\cr
#' UniProt maps proteomics peptides from different sources to the proteins'
#' sequences. Using this function, you can search for proteomics
#' peptides that has been map to UniProt proteins. You may also refine your
#' search with modifiers such as data_source, peptide etc. See
#' "Arguments section" for more information.
#'
#' Note that this is a search function. Thus, you are not required to fill
#' every argument; You may use whatever combinations of arguments you see
#' fit for your query.
#' \cr see also:
#' \href{https://www.uniprot.org/help/ptm_processing_section}{PTM /
#' Processing section in UniProtKB}
#'
#' @section Corresponding API Resources:
#' "GET https://www.ebi.ac.uk/proteins/api/proteomics-ptm"
#'
#' @param accession \href{https://www.uniprot.org/help/accession_numbers}{
#' UniProtKB primary or secondary accession}(s). You can supply up to 100
#' accession numbers.
#' @param ptm Post-translational modification name
#' @param data_source Proteomics data source. You can choose up to two of:
#' \itemize{
#' \item \href{https://www.uniprot.org/database/DB-0186}{"MaxQB"}
#' \item \href{https://www.uniprot.org/database/DB-0071}{"PeptideAtlas"}
#' \item \href{https://www.uniprot.org/database/DB-0205}{"EPD"}
#' \item \href{https://www.uniprot.org/database/DB-0229}{"ProteomicsDB"}
#' }
#' @param taxid NIH-NCBI \href{https://www.uniprot.org/taxonomy/}{Taxon ID}.
#' You can supply up to 20 taxon IDs.
#' @param upid \href{https://www.uniprot.org/help/proteome_id}{UniProt Proteome
#' identifier (UPID)}. You can supply up to 100 UPIDs.
#' @param peptide Peptide sequence(s). You can supply up to 20 sequences.
#' @param unique Logical: Should the results be filtered based on the
#' Peptide's uniqueness (the fact that a peptide maps to only 1 protein). If
#' TRUE, Only unique peptides will be returned, if FALSE only un-unique
#' peptides will be returned; If NULL (default) the results will not be
#' filtered based on this.
#' @param ... rbioapi option(s). See \code{\link{rba_options}}'s
#' arguments manual for more information on available options.
#'
#' @return A list Where each element correspond to a UniProt protein and
#' post-translational modification are organized under the "features"
#' sub-list.
#'
#' @references \itemize{
#' \item The UniProt Consortium, UniProt: the universal protein
#' knowledgebase in 2021, Nucleic Acids Research, Volume 49, Issue D1,
#' 8 January 2021, Pages D480–D489, https://doi.org/10.1093/nar/gkaa1100
#' \item Andrew Nightingale, Ricardo Antunes, Emanuele Alpi, Borisas
#' Bursteinas, Leonardo Gonzales, Wudong Liu, Jie Luo, Guoying Qi, Edd
#' Turner, Maria Martin, The Proteins API: accessing key integrated protein
#' and genome information, Nucleic Acids Research, Volume 45, Issue W1,
#' 3 July 2017, Pages W539–W544, https://doi.org/10.1093/nar/gkx237
#' \item \href{https://www.ebi.ac.uk/proteins/api/doc/}{Proteins API
#' Documentation}
#' \item \href{https://www.uniprot.org/help/publications}{Citations note
#' on UniProt website}
#' }
#'
#' @examples
#' \dontrun{
#' #Deprecated
#' rba_uniprot_ptm_search(peptide = "NDQVYQPLRDRDDAQYSHLGGNWAR")
#' }
#'
#' @family "Deprecated functions"
#' @export
rba_uniprot_ptm_search <- function(accession = NULL,
ptm = NULL,
data_source = NULL,
taxid = NULL,
upid = NULL,
peptide = NULL,
unique = NULL,
...) {
.Deprecated("rba_uniprot_proteomics_ptm_search")
## Load Global Options
.rba_ext_args(...)
## Check User-input Arguments
.rba_args(
cons = list(
list(arg = "accession", class = "character", max_len = 100),
list(arg = "ptm", class = "character", len = 1),
list(arg = "taxid", class = "numeric", max_len = 20),
list(arg = "upid", class = "character", max_len = 100),
list(
arg = "data_source", class = "character", max_len = 2,
val = c("MaxQB", "PeptideAtlas", "EPD", "ProteomicsDB")
),
list(arg = "peptide", class = "character", max_len = 20),
list(arg = "unique", class = "logical")
)
)
.msg(
"Searching UniProt and retrieving proteomics Post-translational modification features of proteins that match your supplied inputs."
)
## Build GET API Request's query
call_query <- .rba_query(
init = list("size" = "-1"),
list("accession", !is.null(accession), paste0(accession, collapse = ",")),
list("ptm", !is.null(ptm), ptm),
list("taxid", !is.null(taxid), paste0(taxid, collapse = ",")),
list("upid", !is.null(upid), paste0(upid, collapse = ",")),
list("data_source", !is.null(data_source), paste0(data_source, collapse = ",")),
list("peptide", !is.null(peptide), paste0(peptide, collapse = ",")),
list("unique", !is.null(unique), ifelse(unique, "true", "false"))
)
## Build Function-Specific Call
parser_input <- list("json->list", .rba_uniprot_search_namer)
input_call <- .rba_httr(
httr = "get",
url = .rba_stg("uniprot", "url"),
path = paste0(.rba_stg("uniprot", "pth"), "proteomics-ptm"),
query = call_query,
accept = "application/json",
parser = parser_input,
save_to = .rba_file("uniprot_ptm_search.json")
)
## Call API
final_output <- .rba_skeleton(input_call)
return(final_output)
}
#' Get Post-Translational Modification of UniProt Protein (Deprecated)
#'
#' This function is Deprecated. Please use
#' \code{\link{rba_uniprot_proteomics_ptm}} instead.\cr
#' UniProt maps post-translational modification features from different sources
#' to the proteins' sequences. Using this function, you can retrieve all
#' the post-translational modification features that has been map to a given
#' UniProt protein's sequence.
#'
#' see also:
#' \href{https://www.uniprot.org/help/ptm_processing_section}{PTM /
#' Processing section in UniProtKB}
#'
#' @section Corresponding API Resources:
#' "GET https://www.ebi.ac.uk/proteins/api/proteomics-ptm/\{accession\}"
#'
#' @param accession \href{https://www.uniprot.org/help/accession_numbers}{
#' UniProtKB primary or secondary accession}.
#' @param ... rbioapi option(s). See \code{\link{rba_options}}'s
#' arguments manual for more information on available options.
#'
#' @return A list containing the post-translational modification features of
#' your supplied UniProt protein's sequence.
#'
#' @references \itemize{
#' \item The UniProt Consortium, UniProt: the universal protein
#' knowledgebase in 2021, Nucleic Acids Research, Volume 49, Issue D1,
#' 8 January 2021, Pages D480–D489, https://doi.org/10.1093/nar/gkaa1100
#' \item Andrew Nightingale, Ricardo Antunes, Emanuele Alpi, Borisas
#' Bursteinas, Leonardo Gonzales, Wudong Liu, Jie Luo, Guoying Qi, Edd
#' Turner, Maria Martin, The Proteins API: accessing key integrated protein
#' and genome information, Nucleic Acids Research, Volume 45, Issue W1,
#' 3 July 2017, Pages W539–W544, https://doi.org/10.1093/nar/gkx237
#' \item \href{https://www.ebi.ac.uk/proteins/api/doc/}{Proteins API
#' Documentation}
#' \item \href{https://www.uniprot.org/help/publications}{Citations note
#' on UniProt website}
#' }
#'
#' @examples
#' \dontrun{
#' #Deprecated
#' rba_uniprot_ptm(accession = "P04234")
#' }
#'
#' @family "Deprecated functions"
#' @export
rba_uniprot_ptm <- function(accession,
...) {
.Deprecated("rba_uniprot_proteomics_ptm")
## Load Global Options
.rba_ext_args(...)
## Check User-input Arguments
.rba_args(
cons = list(list(arg = "accession", class = "character", len = 1)
)
)
.msg(
"Retrieving proteomics Post-translational modification features mapped to the sequence of protein %s.",
accession
)
## Build Function-Specific Call
input_call <- .rba_httr(
httr = "get",
url = .rba_stg("uniprot", "url"),
path = paste0(.rba_stg("uniprot", "pth"), "proteomics-ptm/", accession),
accept = "application/json",
parser = "json->list",
save_to = .rba_file("uniprot_ptm.json")
)
## Call API
final_output <- .rba_skeleton(input_call)
return(final_output)
}
Any scripts or data that you put into this service are public.
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.