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tcplfit2: A Concentration-Response Modeling Utility
The tcplfit2 R package performs basic concentration-response curve fitting. The original tcplFit() function in the tcpl R package performed basic concentration-response curvefitting to 3 models. With tcplfit2, the core tcpl concentration-response functionality has been expanded to process diverse high-throughput screen (HTS) data generated at the US Environmental Protection Agency, including targeted ToxCast, high-throughput transcriptomics (HTTr) and high-throughput phenotypic profiling (HTPP). tcplfit2 can be used independently to support analysis for diverse chemical screening efforts.
Getting started
Browse package contents
Package details |
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| Author | Thomas Sheffield [aut], Richard S Judson [ctb] (<https://orcid.org/0000-0002-2348-9633>), Jason Brown [cre] (<https://orcid.org/0009-0000-2294-641X>), Sarah E. Davidson [ctb] (<https://orcid.org/0000-0002-2891-9380>), Zhihui Zhao [ctb], Madison Feshuk [ctb] (<https://orcid.org/0000-0002-1390-6405>), Katie Paul Friedman [ctb] (<https://orcid.org/0000-0002-2710-1691>) |
| Maintainer | Jason Brown <brown.jason@epa.gov> |
| License | MIT + file LICENSE |
| Version | 0.1.7 |
| URL | https://github.com/USEPA/CompTox-ToxCast-tcplFit2 |
| Package repository | View on CRAN |
| Installation |
Install the latest version of this package by entering the following in R:
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