mc3: Sample concentration-response data set from invitrodb

In tcplfit2: Concentration-Response Modeling of HTS or Transcriptomics Data

Sample concentration-response data set from invitrodb

Description

A data set containing 100 chemicals worth of data for the Tox21 assay TOX21_ERa_BLA_Agonist_ratio, which measures response to estrogen receptor agonists. The data can be accessed further through the Comptox Chemicals Dashboard (https://comptox.epa.gov/dashboard).

Usage

mc3

Format

An object of class data.frame with 32175 rows and 7 columns.

Details

This data is extracted from the released version of the ToxCast database, invitrodb, at level 3 (mc3) and contains the concentration-response information.

A data frame with 32175 rows and 7 variables:

• dtxsid - DSSTox generic substance ID

• casrn - Chemical Abstracts Registry Number (CASRN)

• name - chemical name

• spid - sample ID - there can be multiple samples per chemical

• logc - log10(concentration), micromolar (uM)

• resp - response in %

• assay - name of the assay / assay component endpoint name

Source

\Sexpr[results=rd]{tools:::Rd_expr_doi("https://doi.org/10.23645/epacomptox.6062623.v5")}

tcplfit2 documentation built on Oct. 11, 2023, 1:07 a.m.