hitloginner: Hit Logic Inner (Discrete)

In tcplfit2: Concentration-Response Modeling of HTS or Transcriptomics Data

Hit Logic Inner (Discrete)

Description

Contains hit logic, called directly during CR fitting or later through "hitlogic".

Usage

hitloginner(conc = NULL, resp, top, cutoff, ac50 = NULL)

Arguments

conc	Vector of concentrations (No longer necessary).
resp	Vector of responses.
top	Model top.
cutoff	Desired cutoff.
ac50	Model AC50 (No longer necessary).

Details

The purpose of this function is to keep the actual hit rules in one location so it can be called during CR fitting, and then again after the fact for a variety of cutoffs. Curves fit with constant winning should have top = NA, generating a miss.

Value

Outputs 1 for hit, 0 for miss.

Examples

hitloginner(resp = 1:8, top = 7, cutoff = 5) #hit
hitloginner(resp = 1:8, top = 7, cutoff = 7.5) #miss: top too low
hitloginner(resp = 1:8, top = 9, cutoff = 8.5) #miss: no response> cutoff
hitloginner(resp = 1:8, top = NA, cutoff = 5) #miss: no top (constant)

tcplfit2 documentation built on Oct. 11, 2023, 1:07 a.m.