hitcontinner: Continuous Hitcalls Inner

In tcplfit2: Concentration-Response Modeling of HTS or Transcriptomics Data

Continuous Hitcalls Inner

Description

Calculates continuous hitcall using 3 statistical metrics.

Usage

hitcontinner(conc, resp, top, cutoff, er, ps, fit_method, caikwt, mll)

Arguments

conc	Vector of concentrations.
resp	Vector of responses.
top	Model top.
cutoff	Desired cutoff.
er	Model error parameter.
ps	Vector of used model parameters in order: a, tp, b, ga, p, la, q, er.
fit_method	Name of winning fit method (should never be constant).
caikwt	Akaike weight of constant model relative to winning model.
mll	Maximum log-likelihood of winning model.

Details

This function is called either directly from concRespCore or via hitcont. Details of how to compute function input are in concRespCore.

Value

Continuous hitcall between 0 and 1.

Examples

conc = c(.03,.1,.3,1,3,10,30,100)
resp = c(0,.1,0,.2,.6,.9,1.1,1)
top = 1.023239
er = -3.295307
ps = c(1.033239, 2.453014, 1.592714, er = -3.295307) #tp,ga,p,er
fit_method = "hill"
caikwt = 1.446966e-08
mll = 12.71495
hitcontinner(conc,resp,top,cutoff = 0.8, er,ps,fit_method, caikwt, mll)
hitcontinner(conc,resp,top,cutoff = 1, er,ps,fit_method, caikwt, mll)
hitcontinner(conc,resp,top,cutoff = 1.2, er,ps,fit_method, caikwt, mll)

tcplfit2 documentation built on Oct. 11, 2023, 1:07 a.m.