| abnormal | Count patients with abnormal range values | 
| abnormal_by_baseline | Count patients with abnormal analysis range values by... | 
| abnormal_by_marked | Count patients with marked laboratory abnormalities | 
| abnormal_by_worst_grade | Count patients by most extreme post-baseline toxicity grade... | 
| abnormal_lab_worsen_by_baseline | Count patients with toxicity grades that have worsened from... | 
| add_riskdiff | Split function to configure risk difference column | 
| add_rowcounts | Layout-creating function to add row total counts | 
| aesi_label | Labels for adverse event baskets | 
| afun_riskdiff | Analysis function to calculate risk difference column values | 
| afun_selected_stats | Get selected statistics names | 
| analyze_colvars_functions | Analyze functions in columns | 
| analyze_functions | Analyze functions | 
| analyze_variables | Analyze variables | 
| analyze_vars_in_cols | Analyze numeric variables in columns | 
| append_varlabels | Add variable labels to top left corner in table | 
| apply_auto_formatting | Apply automatic formatting | 
| argument_convention | Standard arguments | 
| arrange_grobs | Arrange multiple grobs | 
| as.rtable | Convert to 'rtable' | 
| assertions | Additional assertions to use with 'checkmate' | 
| bins_percent_labels | Labels for bins in percent | 
| cfun_by_flag | Constructor for content functions given a data frame with... | 
| check_diff_prop_ci | Check proportion difference arguments | 
| check_same_n | Check element dimension | 
| c_label_n | Content row function to add row total to labels | 
| c_label_n_alt | Content row function to add 'alt_counts_df' row total to... | 
| clogit_with_tryCatch | Wrapper function of survival::clogit | 
| combination_function | Class for 'CombinationFunction' | 
| combine_counts | Combine counts | 
| combine_groups | Reference and treatment group combination | 
| combine_vectors | Element-wise combination of two vectors | 
| compare_variables | Compare variables between groups | 
| control_analyze_vars | Control function for descriptive statistics | 
| control_annot | Control functions for Kaplan-Meier plot annotation tables | 
| control_coxph | Control function for Cox-PH model | 
| control_coxreg | Control function for Cox regression | 
| control_incidence_rate | Control function for incidence rate | 
| control_lineplot_vars | Control function for 'g_lineplot()' | 
| control_logistic | Control function for logistic regression model fitting | 
| control_riskdiff | Control function for risk difference column | 
| control_step | Control function for subgroup treatment effect pattern (STEP)... | 
| control_surv_time | Control function for 'survfit' models for survival time | 
| control_surv_timepoint | Control function for 'survfit' models for patients' survival... | 
| count_cumulative | Cumulative counts of numeric variable by thresholds | 
| count_missed_doses | Count number of patients with missed doses by thresholds | 
| count_occurrences | Count occurrences | 
| count_occurrences_by_grade | Count occurrences by grade | 
| count_patients_events_in_cols | Count patient events in columns | 
| count_patients_with_event | Count the number of patients with a particular event | 
| count_patients_with_flags | Count the number of patients with particular flags | 
| count_values | Count specific values | 
| cox_regression | Cox proportional hazards regression | 
| cox_regression_inter | Cox regression helper function for interactions | 
| cut_quantile_bins | Cut numeric vector into empirical quantile bins | 
| day2month | Conversion of days to months | 
| d_count_abnormal_by_baseline | Description function for 's_count_abnormal_by_baseline()' | 
| d_count_cumulative | Description of cumulative count | 
| d_count_missed_doses | Description function that calculates labels for... | 
| decorate_grob | Add titles, footnotes, page Number, and a bounding box to a... | 
| decorate_grob_factory | Update page number | 
| decorate_grob_set | Decorate set of 'grob's and add page numbering | 
| default_na_str | Default string replacement for 'NA' values | 
| default_stats_formats_labels | Get default statistical methods and their associated formats,... | 
| desctools_binom | Confidence intervals for a difference of binomials | 
| df2gg | Convert 'data.frame' object to 'ggplot' object | 
| df_explicit_na | Encode categorical missing values in a data frame | 
| d_onco_rsp_label | Description of standard oncology response | 
| dot-is_equal_float | Utility function to check if a float value is equal to... | 
| d_pkparam | Generate PK reference dataset | 
| d_proportion | Description of the proportion summary | 
| d_proportion_diff | Description of method used for proportion comparison | 
| draw_grob | Draw 'grob' | 
| d_rsp_subgroups_colvars | Labels for column variables in binary response by subgroup... | 
| d_survival_subgroups_colvars | Labels for column variables in survival duration by subgroup... | 
| d_test_proportion_diff | Description of the difference test between two proportions | 
| empty_vector_if_na | Return an empty numeric if all elements are 'NA'. | 
| estimate_coef | Hazard ratio estimation in interactions | 
| estimate_multinomial_rsp | Estimate proportions of each level of a variable | 
| estimate_proportion | Proportion estimation | 
| ex_data | Simulated CDISC data for examples | 
| explicit_na | Missing data | 
| extract_by_name | Extract elements by name | 
| extract_rsp_biomarkers | Prepare response data estimates for multiple biomarkers in a... | 
| extract_rsp_subgroups | Prepare response data for population subgroups in data frames | 
| extract_survival_biomarkers | Prepare survival data estimates for multiple biomarkers in a... | 
| extract_survival_subgroups | Prepare survival data for population subgroups in data frames | 
| extreme_format | Format extreme values | 
| factor_utils | Factor utilities | 
| f_conf_level | Utility function to create label for confidence interval | 
| fit_coxreg | Fitting functions for Cox proportional hazards regression | 
| fit_logistic | Fit for logistic regression | 
| fit_rsp_step | Subgroup treatment effect pattern (STEP) fit for binary... | 
| fit_survival_step | Subgroup treatment effect pattern (STEP) fit for survival... | 
| forest_viewport | Create a viewport tree for the forest plot | 
| format_auto | Format automatically using data significant digits | 
| format_count_fraction | Format count and fraction | 
| format_count_fraction_fixed_dp | Format count and percentage with fixed single decimal place | 
| format_count_fraction_lt10 | Format count and fraction with special case for count < 10 | 
| format_extreme_values | Format a single extreme value | 
| format_extreme_values_ci | Format extreme values part of a confidence interval | 
| format_fraction | Format fraction and percentage | 
| format_fraction_fixed_dp | Format fraction and percentage with fixed single decimal... | 
| format_fraction_threshold | Format fraction with lower threshold | 
| format_sigfig | Format numeric values by significant figures | 
| formatting_functions | Formatting functions | 
| format_xx | Format XX as a formatting function | 
| f_pval | Utility function to create label for p-value | 
| g_bland_altman | Bland-Altman plot | 
| get_covariates | Utility function to return a named list of covariate names | 
| get_smooths | Smooth function with optional grouping | 
| g_forest | Create a forest plot from an 'rtable' | 
| g_ipp | Individual patient plots | 
| g_km | Kaplan-Meier plot | 
| g_lineplot | Line plot with optional table | 
| groups_list_to_df | Convert list of groups to a data frame | 
| g_step | Create a STEP graph | 
| g_waterfall | Horizontal waterfall plot | 
| h_adlb_abnormal_by_worst_grade | Helper function to prepare ADLB for... | 
| h_adlb_worsen | Helper function to prepare ADLB with worst labs | 
| h_adsl_adlb_merge_using_worst_flag | Helper function for deriving analysis datasets for select... | 
| h_ancova | Helper function to return results of a linear model | 
| h_append_grade_groups | Helper function for 's_count_occurrences_by_grade()' | 
| h_biomarkers_subgroups | Helper functions for tabulation of a single biomarker result | 
| h_col_indices | Obtain column indices | 
| h_count_cumulative | Helper function for 's_count_cumulative()' | 
| h_cox_regression | Helper functions for Cox proportional hazards regression | 
| h_data_plot | Helper function to tidy survival fit data | 
| h_decompose_gg | 'ggplot' decomposition | 
| h_format_row | Helper function to format the optional 'g_lineplot' table | 
| h_ggkm | Helper function to create a KM plot | 
| h_g_ipp | Helper function to create simple line plot over time | 
| h_glm_count | Helper functions for Poisson models | 
| h_grob_coxph | Helper function to create Cox-PH grobs | 
| h_grob_median_surv | Helper function to create survival estimation grobs | 
| h_grob_tbl_at_risk | Helper function to create patient-at-risk grobs | 
| h_grob_y_annot | Helper function to create grid object with y-axis annotation | 
| h_incidence_rate | Helper functions for incidence rate | 
| h_km_layout | Helper function to prepare a KM layout | 
| h_logistic_regression | Helper functions for multivariate logistic regression | 
| h_map_for_count_abnormal | Helper function to create a map data frame for... | 
| h_odds_ratio | Helper functions for odds ratio estimation | 
| h_pkparam_sort | Sort pharmacokinetic data by 'PARAM' variable | 
| h_ppmeans | Function to return the estimated means using predicted... | 
| h_prop_diff | Helper functions to calculate proportion difference | 
| h_prop_diff_test | Helper functions to test proportion differences | 
| h_proportions | Helper functions for calculating proportion confidence... | 
| h_response_biomarkers_subgroups | Helper functions for tabulating biomarker effects on binary... | 
| h_response_subgroups | Helper functions for tabulating binary response by subgroup | 
| h_split_by_subgroups | Split data frame by subgroups | 
| h_split_param | Split parameters | 
| h_stack_by_baskets | Helper function to create a new SMQ variable in ADAE by... | 
| h_step | Helper functions for subgroup treatment effect pattern (STEP)... | 
| h_survival_biomarkers_subgroups | Helper functions for tabulating biomarker effects on survival... | 
| h_survival_duration_subgroups | Helper functions for tabulating survival duration by subgroup | 
| h_tbl_coxph_pairwise | Helper function for generating a pairwise Cox-PH table | 
| h_tbl_median_surv | Helper function for survival estimations | 
| h_worsen_counter | Helper function to analyze patients for... | 
| h_xticks | Helper function to calculate x-tick positions | 
| imputation_rule | Apply 1/3 or 1/2 imputation rule to data | 
| incidence_rate | Incidence rate estimation | 
| labels_or_names | Labels or names of list elements | 
| labels_use_control | Update labels according to control specifications | 
| logistic_regression_cols | Logistic regression multivariate column layout function | 
| logistic_summary_by_flag | Logistic regression summary table | 
| make_names | Make names without dots | 
| month2day | Conversion of months to days | 
| muffled_car_anova | Muffled 'car::Anova' | 
| n_available | Number of available (non-missing entries) in a vector | 
| odds_ratio | Odds ratio estimation | 
| prop_diff | Proportion difference estimation | 
| prop_diff_test | Difference test for two proportions | 
| prune_occurrences | Occurrence table pruning | 
| range_noinf | Re-implemented 'range()' default S3 method for numerical... | 
| reapply_varlabels | Reapply variable labels | 
| response_biomarkers_subgroups | Tabulate biomarker effects on binary response by subgroup | 
| response_subgroups | Tabulate binary response by subgroup | 
| rtable2gg | Convert 'rtable' objects to 'ggplot' objects | 
| rtables_access | Helper functions for accessing information from 'rtables' | 
| sas_na | Convert strings to 'NA' | 
| s_bland_altman | Bland-Altman analysis | 
| score_occurrences | Occurrence table sorting | 
| s_cox_multivariate | Multivariate Cox model - summarized results | 
| split_cols_by_groups | Split columns by groups of levels | 
| split_text_grob | Split text according to available text width | 
| stack_grobs | Stack multiple grobs | 
| stat_mean_ci | Confidence interval for mean | 
| stat_mean_pval | p-Value of the mean | 
| stat_median_ci | Confidence interval for median | 
| stat_propdiff_ci | Proportion difference and confidence interval | 
| strata_normal_quantile | Helper function for the estimation of stratified quantiles | 
| study_arm | Indicate study arm variable in formula | 
| summarize_ancova | Summarize analysis of covariance (ANCOVA) results | 
| summarize_change | Summarize change from baseline values or absolute baseline... | 
| summarize_colvars | Summarize variables in columns | 
| summarize_functions | Summarize functions | 
| summarize_glm_count | Summarize Poisson negative binomial regression | 
| summarize_logistic | Multivariate logistic regression table | 
| summarize_num_patients | Count number of patients | 
| summarize_patients_exposure_in_cols | Count number of patients and sum exposure across all patients... | 
| survival_biomarkers_subgroups | Tabulate biomarker effects on survival by subgroup | 
| survival_coxph_pairwise | Analyze a pairwise Cox-PH model | 
| survival_duration_subgroups | Tabulate survival duration by subgroup | 
| survival_time | Survival time analysis | 
| survival_timepoint | Survival time point analysis | 
| tern-package | tern Package | 
| tidy_coxreg | Custom tidy methods for Cox regression | 
| tidy.glm | Custom tidy method for binomial GLM results | 
| tidy.step | Custom tidy method for STEP results | 
| to_n | Replicate entries of a vector if required | 
| to_string_matrix | Convert table into matrix of strings | 
| try_car_anova | 'tryCatch' around 'car::Anova' | 
| univariate | Univariate formula special term | 
| unlist_and_blank_na | Blank for missing input | 
| update_weights_strat_wilson | Helper function for the estimation of weights for... | 
| util_handling_additional_fun_params | Utilities to handle extra arguments in analysis functions | 
| utils_split_funs | Custom split functions | 
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