FilterNetwork: Filter network

In xseq: Assessing Functional Impact on Gene Expression of Mutations in Cancer

Description

Filter network

Usage

FilterNetwork(net, weight, min.weight = 0.8, min.conn.strength = 0.4,
  min.num.conn = 5, max.num.conn = 50, remove.self.connection = TRUE,
  debug = FALSE)

Arguments

net	List, a gene interaction network
weight	The weights of genes, could from the function EstimateExpression
min.weight	Filter the connected genes with weights less than min.weight
min.conn.strength	The minimum gene connection strength
min.num.conn	The minimum number of connections required for a gene to be considered for trans-analysis
max.num.conn	Only keep the top max.conn genes
remove.self.connection	Logical, whether removing self-connections or not
debug	Logical, specifying whether debug information should be printed

Value

The filtered network

Examples

data(net)
net.filt = FilterNetwork(net)

xseq documentation built on May 1, 2019, 9:47 p.m.