InteractionProgramSignificance | R Documentation |
Test Interaction program statistical significance
InteractionProgramSignificance(ip_data, n.replicate = 10000, min.members = 1)
ip_data |
Interaction program data, ie. the output of either |
n.replicate |
Number of one-sided Mann-Whitney tests to perform to assess correlation of each module. Default: 10000 |
min.members |
Minimum number of unique ligands or receptors in order to keep a module. Default: 1. Ie, if a module contains many ligand-receptor pairs that all share the same single ligand, this module will be discarded |
Returns a data.frame of all significant modules, their connectivity p-values for each sample, and their intramodular connectivity in each sample
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