detectEnrichmentOfMutants: Perform a Fisher's Exact test to detect groups enriched with...

In J0bbie/R2CPCT: Misc. functions to perform import and analysis of WGS and RNA-Seq samples

Description

Perform a Fisher's Exact test to detect groups enriched with mutants (mutations / deep CNA).

Usage

detectEnrichmentOfMutants(
  mutData,
  groupInfo,
  genesOfInterest,
  minRelMutantsInGroup = 0.1
)

Arguments

mutData	(tibble): Combinedreport containing the somatic mutations per gene, per sample.
groupInfo	(tibble): Tibble containing grouping information. Needs the following columns: sample, group.
genesOfInterest	(character): List of genes (ENSEMBL/SYMBOL) for which to always look for enrichment (regardless of minRel mutants.)
minRelMutantsInGroup	(numeric): Only check enrichment for genes with >=X rel. mutants in the group.

Value

(tibble) Returns a tibble of the results from the Fisher's Exact test.

J0bbie/R2CPCT documentation built on Feb. 24, 2022, 8:15 a.m.