runModels: runModels runs miRNA mrna model model for various miRNA-mRNA...

In Mercedeh66/mirTarRnaSeq: mirTarRnaSeq

runModels runs miRNA mrna model model for various miRNA-mRNA data distributions

Description

This function defines the boundaries of mRNA vs miRNAs of interest to be analysed by the runModels function

Usage

runModels(
  combination,
  select_mRNA,
  select_miRNA,
  mode = NULL,
  family = glm_poisson(),
  scale = 1,
  cutoff = 0.05,
  all_coeff = NULL
)

Arguments

combination	the combined file for mRNA and selected miRNAs output of combiner function
select_mRNA	the output of gene_variant function.
select_miRNA	The vector of miRNA/s to be investigated.
mode	the mode of analysis if more than one miRNA is being investigated multivariate "multi" or co-variate/interaction analysis "inter" is being used
family	gaussian or poisson
scale	factor to scale input data (for genes) by, prior to rounding and model fitting. (scale must be greater than zero).
cutoff	p-value cut off to call significance
all_coeff	if true only models with all negative coefficients will be selected if false at least one

Value

A list of p-vlaues, annova, and significance for each gene and the miRNA/s of interest

Examples

x <- runModels(Combine, geneVariant, "ebv-mir-bart9-5p")

Mercedeh66/mirTarRnaSeq documentation built on April 14, 2023, 6:49 a.m.