findClosestCOSMIC30andCombinations_withSimilarity: Find closest COSMIC30 signatures or combination of COSMIC30

In Nik-Zainal-Group/signature.tools.lib: signature.tools.lib

Find closest COSMIC30 signatures or combination of COSMIC30

Description

Compares a set of signatures to the COSMIC30 signatures or the simple sum of all combinations of two COSMIC signatures and returns the list of signatures identified and the corresponding similarity. For example, list(cosmic = c("C1","C3","C2+C13"),cos_sim = c(0.94,0.85,0.7)) means that Cosmic (C) signatures 1, 3 and 2+13 were found, while the corrsponding similarities to those signatures are 0.94, 0.85 and 0.7

Usage

findClosestCOSMIC30andCombinations_withSimilarity(sigs)

Arguments

sigs	matrix with 96-channel substitution signatures as columns

Value

the list of signatures identified and corresponding similarities

Nik-Zainal-Group/signature.tools.lib documentation built on April 13, 2025, 5:50 p.m.