Selector: Select signatures from candidate list (according to the...

In WubingZhang/MAGeCKFlute: Integrative Analysis Pipeline for Pooled CRISPR Functional Genetic Screens

Select signatures from candidate list (according to the consistence in most samples).

Description

Select signatures from candidate list (according to the consistence in most samples).

Usage

Selector(mat, cutoff = 0, type = "<", select = 0.8)

Arguments

mat	A matrix, each row is candidates (genes), each column is samples.
cutoff	Numeric, specifying the cutoff to define the signatures.
type	Character, ">" or "<".
select	Numeric, specifying the proportion of samples in which signature is selected.

Value

An list containing two elements, the first is the selected signature and the second is a ggplot object.

Examples

mat = matrix(rnorm(1000*30), 1000, 30)
rownames(mat) = paste0("Gene", 1:1000)
colnames(mat) = paste0("Sample", 1:30)
hits = Selector(mat, select = 0.68)
print(hits$p)

WubingZhang/MAGeCKFlute documentation built on Jan. 27, 2024, 2:43 p.m.