DiscreteEVF: Generating EVFs for cells sampled from tip populations from a...

In YosefLab/SymSim: Simulate Single Cell RNA Sequencing Data

Generating EVFs for cells sampled from tip populations from a tree

Description

Generating EVFs for cells sampled from tip populations from a tree

Usage

DiscreteEVF(
  phyla,
  ncells_total,
  min_popsize,
  i_minpop,
  Sigma,
  n_nd_evf,
  n_de_evf,
  vary,
  evf_center,
  seed
)

Arguments

phyla	tree for cell developement
ncells_total	number of cells from all populations
min_popsize	size of the rarest population
i_minpop	to specify which population has the smallest size
Sigma	The standard deviation of the brownian motion of EVFs changing along the tree
n_nd_evf	number of non-Diff EVFs
n_de_evf	number of Diff EVFs
vary	which parameters are affected by Diff-EVFs. Can be "kon", "koff", "s", "all", "except_kon", "except_koff", "except_s". Suggestions are "all" or "s"
evf_center	the value used to generated evf means. Suggested value is 1
seed	the random seed

Value

a list of two object, one is the evf, and the other is a dataframe indicating the population each cell comes from (pop)

YosefLab/SymSim documentation built on Sept. 30, 2024, 2:22 p.m.