GeneEffects: Getting GeneEffects matrices

In YosefLab/SymSim: Simulate Single Cell RNA Sequencing Data

Getting GeneEffects matrices

Description

This function randomly generates the effect size of each evf on the dynamic expression parameters

Usage

GeneEffects(
  ngenes,
  nevf,
  randseed,
  prob,
  geffect_mean,
  geffect_sd,
  evf_res,
  is_in_module
)

Arguments

ngenes	number of genes
nevf	number of evfs
prob	the probability that the effect size is not 0
geffect_mean	the mean of the normal distribution where the non-zero effect sizes are dropped from
geffect_sd	the standard deviation of the normal distribution where the non-zero effect sizes are dropped from
evf_res	the EVFs generated for cells
is_in_module	a vector of length ngenes. 0 means the gene is not in any gene module. In case of non-zero values, genes with the same value in this vector are in the same module.
randomseed	(should produce same result if ngenes, nevf and randseed are all the same)

Value

a list of 3 matrices, each of dimension ngenes * nevf

YosefLab/SymSim documentation built on Sept. 30, 2024, 2:22 p.m.