Get_params2: Getting the parameters for simulating gene expression from...

In YosefLab/SymSim: Simulate Single Cell RNA Sequencing Data

Getting the parameters for simulating gene expression from EVf and gene effects

Description

This function takes gene_effect and EVF, take their dot product and scale the product to the correct range by using first a logistic function and then adding/dividing by constant to their correct range

Usage

Get_params2(gene_effects, evf, bimod, ranges)

Arguments

gene_effects	a list of three matrices (generated using the GeneEffects function), each corresponding to one kinetic parameter. Each matrix has nevf columns, and ngenes rows.
evf	a vector of length nevf, the cell specific extrinsic variation factor
bimod	the bimodality constant
param_realdata	the fitted parameter distribution to sample from

Value

params a matrix of ngenes * 3

Examples

Get_params()

YosefLab/SymSim documentation built on Sept. 30, 2024, 2:22 p.m.