Get_params: Getting the parameters for simulating gene expression from...
View source: R/simulation_functions.R
| Get_params | R Documentation |
Getting the parameters for simulating gene expression from EVf and gene effects
Description
This function takes gene_effect and EVF, take their dot product and scale the product to the correct range by using first a logistic function and then adding/dividing by constant to their correct range
Usage
Get_params(gene_effects, evf, match_param_den, bimod, scale_s)
Arguments
gene_effects |
a list of three matrices (generated using the GeneEffects function), each corresponding to one kinetic parameter. Each matrix has nevf columns, and ngenes rows. |
evf |
a vector of length nevf, the cell specific extrinsic variation factor |
match_param_den |
the fitted parameter distribution density to sample from |
bimod |
the bimodality constant |
scale_s |
a factor to scale the s parameter, which is used to tune the size of the actual cell (small cells have less number of transcripts in total) |
Value
params a matrix of ngenes * 3
Examples
Get_params()
