get_D_KL_continuous_highD: Calculates the Kullback-Leibler divergence between...

In alexisvdb/singleCellHaystack: A Universal Differential Expression Prediction Tool for Single-Cell and Spatial Genomics Data

Calculates the Kullback-Leibler divergence between distributions for the high-dimensional continuous version of haystack.

Description

Calculates the Kullback-Leibler divergence between distributions for the high-dimensional continuous version of haystack.

Usage

get_D_KL_continuous_highD(
  weights,
  density.contributions,
  reference.prob,
  pseudo = 0
)

Arguments

weights	A numerical vector with expression values of a gene.
density.contributions	A matrix of density contributions of each cell (rows) to each center point (columns).
reference.prob	A reference distribution to calculate the divergence against.
pseudo	A pseudocount, used to avoid log(0) problems.

Value

A numerical value, the Kullback-Leibler divergence

alexisvdb/singleCellHaystack documentation built on Jan. 17, 2024, 10:45 a.m.