get_D_KL_highD: Calculates the Kullback-Leibler divergence between...

In alexisvdb/singleCellHaystack: A Universal Differential Expression Prediction Tool for Single-Cell and Spatial Genomics Data

Calculates the Kullback-Leibler divergence between distributions for the high-dimensional version of haystack().

Description

Calculates the Kullback-Leibler divergence between distributions for the high-dimensional version of haystack().

Usage

get_D_KL_highD(classes, density.contributions, reference.prob, pseudo = 0)

Arguments

classes	A logical vector. Values are T is the gene is expressed in a cell, F is not.
density.contributions	A matrix of density contributions of each cell (rows) to each center point (columns).
reference.prob	A reference distribution to calculate the divergence against.
pseudo	A pseudocount, used to avoid log(0) problems.

Value

A numerical value, the Kullback-Leibler divergence

alexisvdb/singleCellHaystack documentation built on Jan. 17, 2024, 10:45 a.m.