| adjustMet1 | Phase II efficacy estimates/Phase III sample size adjustment... |
| adjustMet2 | Phase III sample size adjustment factor (Method 2). |
| AnalyzeEKOAD | Analyze simulated adaptive trials. |
| AnalyzePerformanceSimon | Performance of estimation methods |
| AnalyzePerformanceSimon2 | Performance of estimation methods |
| AnalyzeSimonDsgn | Analysis of simulated Simon's design trials |
| AnalyzeSimonDsgnAdaptN | Analysis of simulated adaptive Simon's design trials |
| AnIItoIIIRe | Use of Phase II estimates to plan Phase III sample size. |
| aop1 | Overall p-value (Method 1 of Nhacolo and Brannath, 2018). |
| aop1e | Overall p-value for CI (Method 1 of Nhacolo and Brannath,... |
| aop2 | Overall p-value (Method 2 of Nhacolo and Brannath, 2018). |
| aop2e | Overall p-value for CI (Method 2 of Nhacolo and Brannath,... |
| aop2ev2 | Overall p-value for CI (Method 2v2 of Nhacolo and Brannath,... |
| aop2v2 | Overall p-value (Method 2v2 of Nhacolo and Brannath, 2018). |
| aop3e | Overall p-value (Method 3 of Nhacolo and Brannath, 2018). |
| CalculateSimonDsgn | Simon's designs |
| checkMonoDCF | Check the monotonicity of the sample space ordering. |
| ci1 | Confidence interval (using Method 1 of Nhacolo and Brannath,... |
| ci2 | Confidence interval (using Method 2 of Nhacolo and Brannath,... |
| ci2v2 | Confidence interval (using Method 2v2 of Nhacolo and... |
| ci3 | Confidence interval (using Method 3 of Nhacolo and Brannath,... |
| dsgnPrep | Pre-process the Englert and Kieser (2013) optimal adaptive... |
| EKOADwn | Pre-processed Englert and Kieser (2013)'s optimal adaptive... |
| EKOptAdaptDesigns | Englert and Kieser (2013)'s optimal adaptive designs. |
| getN2v2 | Number of patients to be enrolled in the second stage |
| mue1 | Median estimate (using Method 1 of Nhacolo and Brannath,... |
| mue2 | Median estimate (using Method 2 of Nhacolo and Brannath,... |
| mue2v2 | Median estimate (using Method 2v2 of Nhacolo and Brannath,... |
| mue3 | Median estimate (using Method 3 of Nhacolo and Brannath,... |
| Nct | Sample size per group for single-stage parallel-group RCT. |
| pdata | Helper function for analyzing the performance of estimators |
| pdata2 | Helper function for analyzing the performance of estimators |
| PerforIItoIIIRe | Performance, with respect to Phase III power, of phase II... |
| PerformanceEKOAD | Performance of estimation methods |
| pg | Bias-reduced estimator |
| pipv1 | Response rate to attain a specified p-value (using Method 1... |
| pipv2 | Response rate to attain a specified p-value (using Method 2... |
| pipv2v2 | Response rate to attain a specified p-value (using Method 2v2... |
| pipv3 | Response rate to attain a specified p-value (using Method 3... |
| pk | Median unbiased estimator |
| pm | Sample proportion |
| pp | UMVCUE |
| pquantile | Value of response rate to attain a given p-value |
| pu | UMVUE |
| pvaluek | P-value |
| Pwr | Power for single-stage parallel-group RCT. |
| sbias | Bias of the sample proportion |
| sfms | Probability mass function of '(M, S)' |
| SimulateEKOAD | Simulate single-arm binary endpoint two-stage adaptive... |
| SimulateSimonDsgn | Simon's designs data simulation |
| SimulateSimonDsgnAdaptN | Simon's adaptive designs data simulation |
