pipv2v2: Response rate to attain a specified p-value (using Method 2v2...
In arsenionhacolo/InferenceBEAGSD: Inference for Binary Endpoint Adaptive Group-Sequential Designs
Description
Usage
Arguments
Details
Value
Author(s)
References
See Also
Description
pipv2v2 finds the response probability under the null hypotheisis that,
given the observed data, would yield a desired overall p-value.
Usage
1
pipv2v2(dsgn, x1o, xo, pv)
Arguments
dsgn
Dataframe containing one of the designs in EKOADwn.
x1o
The observed stage 1 number of responses.
xo
The total observed number of responses.
pv
The desired p-value.
Details
The p-value is obtained using the Method 2v2, one of the four methods proposed by
Nhacolo and Brannath (2018) primarily for single-arm adaptive two-stage group sequential
designs with a binary endpoint.
Value
Response probability.
Author(s)
Arsenio Nhacolo
References
Nhacolo, A. and Brannath, W. Interval and point estimation in adaptive Phase II trials with binary endpoint.
Stat Methods Med Res, 2018.
See Also
pipv1, pipv2, pipv3, aop2v2, aop2ev2.
arsenionhacolo/InferenceBEAGSD documentation built on May 9, 2019, 4:10 a.m.
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Description Usage Arguments Details Value Author(s) References See Also
Description
pipv2v2 finds the response probability under the null hypotheisis that,
given the observed data, would yield a desired overall p-value.
Usage
1 | pipv2v2(dsgn, x1o, xo, pv)
|
Arguments
dsgn |
Dataframe containing one of the designs in |
x1o |
The observed stage 1 number of responses. |
xo |
The total observed number of responses. |
pv |
The desired p-value. |
Details
The p-value is obtained using the Method 2v2, one of the four methods proposed by Nhacolo and Brannath (2018) primarily for single-arm adaptive two-stage group sequential designs with a binary endpoint.
Value
Response probability.
Author(s)
Arsenio Nhacolo
References
Nhacolo, A. and Brannath, W. Interval and point estimation in adaptive Phase II trials with binary endpoint. Stat Methods Med Res, 2018.
See Also
pipv1, pipv2, pipv3, aop2v2, aop2ev2.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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