Description Usage Arguments Details Value Author(s) References See Also
mue2v2
calculates the median estimate of the response rate.
1 | mue2v2(dsgn, x1o, xo)
|
dsgn |
Dataframe containing one of the designs in |
x1o |
The observed stage 1 number of responses. |
xo |
The total observed number of responses. |
This estimate is obtained using the Method 2v2, one of the four methods proposed by Nhacolo and Brannath (2018) primarily for single-arm adaptive two-stage group sequential designs with a binary endpoint.
Median estimate of response probability.
Arsenio Nhacolo
Nhacolo, A. and Brannath, W. Interval and point estimation in adaptive Phase II trials with binary endpoint. Stat Methods Med Res, 2018.
mue1
, mue2
, mue3
, aop2v2
, aop2ev2
, pipv2v2
.
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