mue2: Median estimate (using Method 2 of Nhacolo and Brannath,...
In arsenionhacolo/InferenceBEAGSD: Inference for Binary Endpoint Adaptive Group-Sequential Designs
Description
Usage
Arguments
Details
Value
Author(s)
References
See Also
Description
mue2 calculates the median estimate of the response rate.
Usage
1
mue2(dsgn, x1o, xo)
Arguments
dsgn
Dataframe containing one of the designs in EKOADwn.
x1o
The observed stage 1 number of responses.
xo
The total observed number of responses.
Details
This estimate is obtained using the Method 2, one of the four methods proposed by
Nhacolo and Brannath (2018) primarily for single-arm adaptive two-stage group sequential
designs with a binary endpoint.
Value
Median estimate of response probability.
Author(s)
Arsenio Nhacolo
References
Nhacolo, A. and Brannath, W. Interval and point estimation in adaptive Phase II trials with binary endpoint.
Stat Methods Med Res, 2018.
See Also
mue1, mue2v2, mue3, aop2, aop2e, pipv2.
arsenionhacolo/InferenceBEAGSD documentation built on May 9, 2019, 4:10 a.m.
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Description Usage Arguments Details Value Author(s) References See Also
Description
mue2 calculates the median estimate of the response rate.
Usage
1 | mue2(dsgn, x1o, xo)
|
Arguments
dsgn |
Dataframe containing one of the designs in |
x1o |
The observed stage 1 number of responses. |
xo |
The total observed number of responses. |
Details
This estimate is obtained using the Method 2, one of the four methods proposed by Nhacolo and Brannath (2018) primarily for single-arm adaptive two-stage group sequential designs with a binary endpoint.
Value
Median estimate of response probability.
Author(s)
Arsenio Nhacolo
References
Nhacolo, A. and Brannath, W. Interval and point estimation in adaptive Phase II trials with binary endpoint. Stat Methods Med Res, 2018.
See Also
mue1, mue2v2, mue3, aop2, aop2e, pipv2.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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