aop1e: Overall p-value for CI (Method 1 of Nhacolo and Brannath,...
In arsenionhacolo/InferenceBEAGSD: Inference for Binary Endpoint Adaptive Group-Sequential Designs
Description
Usage
Arguments
Details
Value
Author(s)
References
See Also
Description
aop1e is a modified version of aop1 used
for getting the confidence interval.
Usage
1
aop1e(dsgn, x1o, xo, newpi0)
Arguments
dsgn
Dataframe containing one of the designs in EKOADwn.
x1o
The observed stage 1 number of responses.
xo
The total observed number of responses.
newpi0
New response probability that replaces the one under the null hypothesis.
Details
This is one of the four methods proposed by Nhacolo and Brannath (2018) primarily
for single-arm adaptive two-stage group sequential designs with a binary endpoint.
Value
p-value.
Author(s)
Arsenio Nhacolo
References
Nhacolo, A. and Brannath, W. Interval and point estimation in adaptive Phase II trials with binary endpoint.
Stat Methods Med Res, 2018.
See Also
arsenionhacolo/InferenceBEAGSD documentation built on May 9, 2019, 4:10 a.m.
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Description Usage Arguments Details Value Author(s) References See Also
Description
aop1e is a modified version of aop1 used
for getting the confidence interval.
Usage
1 | aop1e(dsgn, x1o, xo, newpi0)
|
Arguments
dsgn |
Dataframe containing one of the designs in |
x1o |
The observed stage 1 number of responses. |
xo |
The total observed number of responses. |
newpi0 |
New response probability that replaces the one under the null hypothesis. |
Details
This is one of the four methods proposed by Nhacolo and Brannath (2018) primarily for single-arm adaptive two-stage group sequential designs with a binary endpoint.
Value
p-value.
Author(s)
Arsenio Nhacolo
References
Nhacolo, A. and Brannath, W. Interval and point estimation in adaptive Phase II trials with binary endpoint. Stat Methods Med Res, 2018.
See Also
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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