convertToDosage: Train and predict gene's predictive model with mediators

In bhattacharya-a-bt/MOSTWAS: Multi-Omic Strategies for Transcriptome-Wide Association Studies

Train and predict gene's predictive model with mediators

Description

The function trains a predictive model of a given gene using top mediators as fixed effects and assesses in-sample performance with cross-validation.

Usage

convertToDosage(
  format = "plink",
  fileName,
  doseFile,
  locsFile,
  annotFile,
  append = F
)

Arguments

format	character, 'plink' or 'vcf'
fileName	character, prefix only for plink or vcf files
doseFile	character, output file name for dosage file
locsFile	character, output file name for SNP location file
annotFile	character, output file name for SNP annotation file
append	logical, T/F if we are appending to existing files for large plink/vcf files

Value

final model for gene along with CV R2 and predicted values

bhattacharya-a-bt/MOSTWAS documentation built on April 6, 2023, 12:20 a.m.