sobelTest: Compute total mediation effect
In bhattacharya-a-bt/MOSTWAS: Multi-Omic Strategies for Transcriptome-Wide Association Studies
sobelTest R Documentation
Compute total mediation effect
Description
The function takes in a SNP-mediator set-gene triplet
and computes the total mediation effect and tests
the total mediator effect via a Sobel test (1982)
Usage
sobelTest(snp, expression, mediators, covs)
Arguments
snp
vector, SNP of interest
expression
vector, gene expression of interest
mediators
data frame, mediators of interest
covs
data frame, covariates
Value
estimate of TME and Sobel test P-value
bhattacharya-a-bt/MOSTWAS documentation built on April 6, 2023, 12:20 a.m.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
| sobelTest | R Documentation |
Compute total mediation effect
Description
The function takes in a SNP-mediator set-gene triplet and computes the total mediation effect and tests the total mediator effect via a Sobel test (1982)
Usage
sobelTest(snp, expression, mediators, covs)
Arguments
snp |
vector, SNP of interest |
expression |
vector, gene expression of interest |
mediators |
data frame, mediators of interest |
covs |
data frame, covariates |
Value
estimate of TME and Sobel test P-value
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
Embedding an R snippet on your website
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.