bhatturam/prius: Affected pathway ranking in differential gene expression analysis

An R package to analyse affected pathways in differential expression experiments. The approach is to disturb each node of a gene-gene interaction network proportional to the observed expression from the experiment and rank the pathways based on how much they are affected. The package currently supports microarray data from Gene Expression Omnibus, PPI data from iRef and Reactome and pathways from Reactome.

Getting started

Package details

AuthorShailesh Patil, Bharath Venkatesh, Randeep Singh
Bioconductor views DifferentialExpression GeneExpression Genetics GraphAndNetwork Microarray NetworkEnrichment
MaintainerBharath Venkatesh <bharath.venkatesh85@gmail.com>
LicenseMIT + file LICENSE
Version0.99.0
URL https://github.com/bhatturam/prius
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("bhatturam/prius")
bhatturam/prius documentation built on May 12, 2019, 8:24 p.m.