A_clone | A matrix of read numbers of alternative alleles for clone ID |
A_germline | A matrix of read numbers of alternative alleles |
assign_cells_to_clones | Assign cells to clones from cardelino results |
assign_scores | Scoring the simulation in assignment of singlets and doublets |
binaryPRC | Precision-recall curve for binary label prediction |
binaryROC | ROC curve for binary label prediction |
clone_id | Infer clonal identity of single cells |
colMatch | Column match between two matrices by minimum mean absolute... |
Config_all | A list of tree configuration |
D_clone | A matrix of sequencing depths for clone ID |
devianceIC | Deviance Information Criterion for cardelino model |
D_germline | A matrix of sequencing depths |
D_input | A matrix of sequencing depths |
donor_read_simulator | Reads simulator for donor identification |
get_logLik | Log likelihood of clone_id model It returns P(A, D | C, I,... |
get_snp_matrices | Get SNP data matrices from VCF object(s) |
get_tree | Get a clonal tree from a configuration matrix |
Geweke_Z | Geweke diagnostic for MCMC sampling. |
heatmap.theme | The theme of heatmaps for prob_heatmap and sites_heatmap |
heat_matrix | Plot heatmap from a matrix |
load_cellSNP_vcf | Load sparse matrices A and D from cellSNP VCF file with... |
load_GT_vcf | Load genotype VCF into numeric values: 0, 1, or 2 |
mixBinom | EM algorithm for estimating binomial mixture model |
mtx_to_df | Convert a matrix to data frame |
multiPRC | Precision-recall curve for multi-class prediction |
plot_config_diffs | Define a publication-style plot theme |
plot_tree | Plot a phylogenetic tree |
predMixBinom | Predicted probability from learned binomial mixture model |
prob_heatmap | Plot a heatmap for probability of clone assignment |
pub.theme | Define a publication-style plot theme |
read_vcf | Read a VCF file into R session |
rowArgmax | Column index of the maximum value for each row in a matrix |
rowMax | Maximum value for each row in a matrix |
sample_seq_depth | Update matrix D with manually selected missing rate |
sample_tree_SNV | Down sample number of SNVs in the tree |
sim_read_count | Synthetic reads generator for genetic variants |
tree | A tree object |
tree_3clone | A tree object |
tree_4clone | A tree object |
tree_5clone | A tree object |
vc_heatmap | Plot a variant-cell heatmap for cell clonal assignment |
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