demar01/RIC: RIC (RNA interaction capture)

RIC package automates search for RBP from cRIC (RNA-interactome capture)proteomics experiments. It requires tabular input (i.e. peptides.txt files) generated by MaxQuant software for quantitative analysis of raw mass spectrometry data. It uses QFeatures infrastructure to handle and process high-throughput mass spectrometry data. Functions provided in the package enable bacth correction and peptide aggregation as well as vizualization for intensity distribition across replicates, moderated statistical analysis adjusted for multiple hypothesis testing and scatter and volcano plots visualizations, scatter and volcano plots.

install.packages("remotes")
remotes::install_github("demar01/RIC")