population.pairing: Compute cell-cell interaction network.

View source: R/population.pairing_CellComm.R

population.pairingR Documentation

Compute cell-cell interaction network.

Description

Analyze the mean expression data generated by the computeValue method of CellRouter to determine co-expression patterns of ligands and receptors.

Usage

population.pairing(mean.expr, ligands, receptors, threshold, pairs)

Arguments

mean.expr

list; the statistics of the expressed genes as calculated by the computeValue method of CellRouter.

ligands

vector; list of genes annotated as ligands.

receptors

vector; list of genes annotated as receptors.

threshold

numeric; threshold to select the genes in the population according to their mean expression.

pairs

the pairs;

Value

data frame; interactions with celltype1, celltype2, pair, ligand, and receptor.


edroaldo/fusca documentation built on March 1, 2023, 1:43 p.m.