ranked_findSpecGenes: Helper function of findSignatures.

In edroaldo/fusca: Framework for Unified Single-Cell Analysis

Helper function of findSignatures.

Description

Find gene signatures based on a template-matching approach. Find genes that are preferentially expressed in specified samples. Find it by adjusting a line to the gene expression for each cell population, the getting the most representative genes, the ones with better fit.

Usage

ranked_findSpecGenes(
  expDat,
  sampTab,
  qtile = 0.95,
  remove = FALSE,
  dLevel = "population_name"
)

Arguments

expDat	Expression matrix
sampTab	Sample annotation table
qtile	numeric; quantile (between 0 and 1) to select top genes correlated with the idealized expression pattern.
remove	logical; remove overlaping genes.
dLevel	character; annotation level to group on, groups to compare.

Value

; specificSets.

edroaldo/fusca documentation built on March 1, 2023, 1:43 p.m.