vpres2regulon: Extract the top up and down regulated MR per sample

In fossbert/binilib: Carlo's little helper

Description

Extract the top up and down regulated MR per sample

Usage

vpres2regulon(
  vpres,
  nn = 25,
  direction = c("both", "up", "down"),
  make_regulon = FALSE,
  reverse = FALSE,
  verbose = TRUE
)

Arguments

vpres	numeric matrix of NES as returned by the viper function
nn	integer of number of top MR to consider for each regulon
direction	character, which tail should be returned, defaults to both up and down
make_regulon	logical, whether to set class of return object to "regulon"
reverse,	logical, whether to reverse the top MR - useful for drug screening results and downstream applications
verbose	logical, whether to message progress report

Value

list object with top dysregulated MR per sample

fossbert/binilib documentation built on April 23, 2021, 10:31 p.m.