binom_ci: Calculate enrichment confidence interval.
In ilia-kats/RiboSeqTools: Tools for analysis of selective ribosome profiling (SeRP) data
Description
Usage
Arguments
Details
Value
View source: R/utils_enrichment.R
Description
Given total read counts in two samples, calculates library size-normalized confidence intervals
for the ratio sample1/sample2.
Usage
1
binom_ci(sample1, sample2, sample1_total, sample2_total, conf.level = 0.95)
Arguments
sample1
Read counts in sample1.
sample2
Read counts in sample2.
sample1_total
Total number of reads in sample1 (for library size normalization).
sample2_total
Total number of reads in sample2 (for library size normalization).
conf.level
Confidence level.
Details
Uses the Agresti-Coull approximation to calculate binomial confidence intervals of
sample1/(sample1 + sample2).
These values are then converted to CIs of sample1/sample2
and normalized for library size.
Value
A tibble containing the observed proportions and the lower
and upper bounds of the confidence interval.
ilia-kats/RiboSeqTools documentation built on Oct. 5, 2020, 7:41 p.m.
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Description Usage Arguments Details Value
View source: R/utils_enrichment.R
Description
Given total read counts in two samples, calculates library size-normalized confidence intervals for the ratio sample1/sample2.
Usage
1 | binom_ci(sample1, sample2, sample1_total, sample2_total, conf.level = 0.95)
|
Arguments
sample1 |
Read counts in sample1. |
sample2 |
Read counts in sample2. |
sample1_total |
Total number of reads in sample1 (for library size normalization). |
sample2_total |
Total number of reads in sample2 (for library size normalization). |
conf.level |
Confidence level. |
Details
Uses the Agresti-Coull approximation to calculate binomial confidence intervals of sample1/(sample1 + sample2). These values are then converted to CIs of sample1/sample2 and normalized for library size.
Value
A tibble containing the observed proportions and the lower and upper bounds of the confidence interval.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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