RefineVariableGenes: Update the '@var.genes' slot of a Seurat object using cluster...

Description Usage Arguments Value

View source: R/exploratory_pipeline.R

Description

Update the '@var.genes' slot of a Seurat object using cluster markers.

Usage

1
RefineVariableGenes(dge, log_fc = 1, eligible_genes = NULL)

Arguments

dge

Seurat object

log_fc

For each gene, we compute the difference between the highest and lowest cluster mean. If it exceeds this, the gene is included in the active set.

eligible_genes

dge@var.genes get intersected with this list before return.

Value

A Seurat object.


maehrlab/thymusatlastools documentation built on May 28, 2019, 2:32 a.m.