Find_Target_Max_dES: Do backward random search to find set of targets that...

In ningb/diffreg: Differential Regulation Analysis of miRNAs

Do backward random search to find set of targets that maximize the normalized dES

Description

Do backward random search to find set of targets that maximize the normalized dES

Usage

Find_Target_Max_dES(
  gs,
  cor.list,
  main,
  ref,
  miR,
  direction = c("Negative", "Positive"),
  min.gs.size = 20,
  n.iter = 500,
  alpha = 1
)

Arguments

gs	A character vector for a set of targets. One element from output of GetLE().
cor.list	A matrix from Run_LINE()
main	A character for the name of the group to compared to.
ref	A character for the name of the group to compared to.
miR	A character for the name of the miRNA to bet tested.
direction	A character for the direction of enrichment
min.gs.size	An integer indicating the minimum number of genes to used. Default is 20.
n.iter	An integer indicating the number of background to generate for normlizing ES. Default is 500
alpha	A numeric variable for gsea parameter

Value

A character vector of target names

ningb/diffreg documentation built on Jan. 20, 2025, 4:10 p.m.