dot-initialize_theta: .initialize_theta

In stephaniehicks/methylCC: Estimate the cell composition of whole blood in DNA methylation samples

.initialize_theta

Description

Creates a container with initial theta parameter estimates

Usage

.initialize_theta(n, K, alpha0 = NULL, alpha1 = NULL, sig0 = NULL,
  sig1 = NULL, tau = NULL)

Arguments

n	Number of samples
K	Number of cell types
alpha0	Default NULL. Initial mean methylation level in unmethylated regions
alpha1	Default NULL. Initial mean methylation level in methylated regions
sig0	Default NULL. Initial var methylation level in unmethylated regions
sig1	Default NULL. Initial var methylation level in methylated regions
tau	Default NULL. Initial var for measurement error

Value

A data frame with initial parameter estimates to be used in .initializeMLEs().

stephaniehicks/methylCC documentation built on Nov. 6, 2022, 5:51 p.m.