Description Usage Arguments Value
make design matrix and contrasts based on whether signal_combination is 2 drugs or M/F/Dug
1 | designMatrixAndContrasts(metadata, pipeline, DRUG_COMBINATION = TRUE)
|
metadata |
data.frame with metadata retrieved for 4 conditions |
pipeline |
character vector of length 1 indicating what pipeline is being used to classify interaction modes for each gene |
drug_combination |
Boolean TRUE when signal x, signal y, and signal x + y are conditions 2, 3, and 4 respectively |
list where list[[1]] is the design matrix and list[[2]] represent the contrasts created with limma::make.contrasts if pipeline == "edgeR" if pipeline == "limma", then a design matrix is returned.
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