plierResToMarkers: Creates a binary cell-type marker matrix using prior results....

In wgmao/PLIER: Pathway-Level Information Extractor (PLIER): a generative model for gene expression data

Creates a binary cell-type marker matrix using prior results. This matrix can be used for other downstream tasks that require cell-type markers, such as CellCODE

Description

Creates a binary cell-type marker matrix using prior results. This matrix can be used for other downstream tasks that require cell-type markers, such as CellCODE

Usage

plierResToMarkers(plierRes, priorMat, num = 20, index = NULL)

Arguments

plierRes	A PLIER result
priorMat	the binary prior information matrix that was used to compute the plierResult. Including this insures that only the genes annotated to the pathway(s) are included
num	The number of marker genes to produce
index	The indecies of PLIER latent variables that are believed to represent cell-type proportions (as opposed to other sources of correlation)

wgmao/PLIER documentation built on May 11, 2022, 10:34 p.m.