module_Validate: module_Validate

Description Usage Arguments Value Author(s) Examples

View source: R/miRSM.R

Description

Validation of miRNA sponge interactions in each miRNA sponge module

Usage

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module_Validate(Modulelist, Groundtruth)

Arguments

Modulelist

List object: a list of the identified miRNA sponge modules.

Groundtruth

Matrix object: a list of experimentally validated miRNA sponge interactions.

Value

List object: a list of validated miRNA sponge interactions in each miRNA sponge module

Author(s)

Junpeng Zhang (https://www.researchgate.net/profile/Junpeng_Zhang3)

Examples

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data(BRCASampleData)
modulegenes_WGCNA <- module_WGCNA(ceRExp, mRExp)
# Identify miRNA sponge modules using sensitivity RV coefficient (SRVC)
miRSM_WGCNA_SRVC <- miRSM(miRExp, ceRExp, mRExp, miRTarget,
                        modulegenes_WGCNA, method = "SRVC",
                        SMC.cutoff = 0.01, RV_method = "RV")
miRSM_WGCNA_SRVC_genes <- miRSM_WGCNA_SRVC[[2]]
library(miRspongeR)
Groundtruthcsv <- system.file("extdata", "Groundtruth.csv", package="miRspongeR")
Groundtruth <- read.csv(Groundtruthcsv, header=TRUE, sep=",") 
miRSM.Validate <- module_Validate(miRSM_WGCNA_SRVC_genes, Groundtruth)

zhangjunpeng411/miRSM documentation built on Nov. 28, 2020, 7 a.m.