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Performs ratio, GC content correction and normalization of data obtained using low coverage (one read every 100-10,000 bp) high troughput sequencing. It performs a "discrete" normalization looking for the ploidy of the genome. It will also provide tumour content if at least two ploidy states can be found.
Package details |
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Author | Stefano Berri <sberri@illumina.com>, Henry M. Wood <H.M.Wood@leeds.ac.uk>, Arief Gusnanto <a.gusnanto@leeds.ac.uk> |
Bioconductor views | CopyNumberVariation Coverage DNASeq GenomicVariation Normalization Sequencing WholeGenome |
Maintainer | Stefano Berri <sberri@illumina.com> |
License | GPL-2 |
Version | 1.36.0 |
URL | http://www.r-project.org |
Package repository | View on Bioconductor |
Installation |
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