CNAnorm: A normalization method for Copy Number Aberration in cancer samples

Performs ratio, GC content correction and normalization of data obtained using low coverage (one read every 100-10,000 bp) high troughput sequencing. It performs a "discrete" normalization looking for the ploidy of the genome. It will also provide tumour content if at least two ploidy states can be found.

Getting started

Package details

AuthorStefano Berri <sberri@illumina.com>, Henry M. Wood <H.M.Wood@leeds.ac.uk>, Arief Gusnanto <a.gusnanto@leeds.ac.uk>
Bioconductor views CopyNumberVariation Coverage DNASeq GenomicVariation Normalization Sequencing WholeGenome
MaintainerStefano Berri <sberri@illumina.com>
LicenseGPL-2
Version1.36.0
URL http://www.r-project.org
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("CNAnorm")

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CNAnorm documentation built on Nov. 8, 2020, 5:29 p.m.